Leukemia. These authors examined the effects of six xanthones extracted from the pericarps of the mangosteen fruit, Garcinia mangostana, on the cell growth inhibition of human leukemia cellline HL60. All xanthones displayed growth inhibitory effects. Among them, alpha-mangostin (a xanthone) showed the most potent ability to cause the cancer cells death.

Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.
Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M, Nozawa Y. Gifu
International Institute of Biotechnology, 1-1 Naka-Fudogaoka, Kakamigahara, Gifu 504-
0838, Japan.

A Summary of 31 Mangosteen Studies
Introduction: Narace D. Seudeal, Ph.D. is a Ph.D. in Clinical Biochemistry who refuses to accept products without the research to back them up — meaning actual clinical and scientific studies rather than weak tests that have no real relevance to the human condition. Mangosteen xanthones research is extensive and studied by Ph.D.’s, MD’s, and other research scientists from around the world. Dr. Seudeal reviewed 31 selections of mangosteen xanthones research articles and condensed the main conclusions in an easy-to-read format with the least technical jargon as possible, yet keeping the integrity of the medical findings intact. Remember, this is just a sampling of xanthones research. There are over 1500 papers on xanthones listed at www.pubmed.gov, the National Medical Library. For hundreds of years, Asian natives used the mangosteen fruit to treat a variety of sicknesses and conditions, without any clue as to the nature of the active ingredients in their concoctions using the mangosteen fruit or why they worked. Today, because of the mangosteen xanthones research done worldwide, we can understand why the potions, preparations, and poultices used by
the natives of Asia were effective enough to endure through time. 31 Mangosteen Research Studies Summarized by Narace D. Seudeal, Ph.D.

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