Allergies. The fruit hull of mangosteen, Garcinia mangostana L., mangosteen fruit, has been used as a Thai indigenous medicine for many years. However, its mechanism of action as a medicine has not been elucidated. The present study was undertaken to examine the effects of mangosteen fruit extracts on histamine release and prostaglandin E2 synthesis. The investigators found the mangosteen fruit extract strongly inhibited histamine release and prostaglandin E2 synthesis. This has great importance in preventing allergies.
Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull. 2002 Sep;25(9):1137-41. Nakatani K, Atsumi M, Arakawa T, Oosawa K, Shimura S, Nakahata N, Ohizumi Y. Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
A Summary of 31 Mangosteen Studies
Introduction: Narace D. Seudeal, Ph.D. is a Ph.D. in Clinical Biochemistry who refuses to accept products without the research to back them up — meaning actual clinical and scientific studies rather than weak tests that have no real relevance to the human condition. Mangosteen xanthones research is extensive and studied by Ph.D.’s, MD’s, and other research scientists from around the world.
Dr. Seudeal reviewed 31 selections of mangosteen xanthones research articles and condensed the main conclusions in an easy-to-read format with the least technical jargon as possible, yet keeping the integrity of the medical findings intact.
Remember, this is just a sampling of xanthones research. There are over 1500 papers on xanthones listed at www.pubmed.gov, the National Medical Library. For hundreds of years, Asian natives used the mangosteen fruit to treat a variety of sicknesses and conditions, without any clue as to the nature of the active ingredients in their concoctions using the mangosteen fruit or why they worked. Today, because of the mangosteen xanthones research done worldwide, we can understand why the potions, preparations, and poultices used by
the natives of Asia were effective enough to endure through time. 31 Mangosteen Research Studies
Summarized by Narace D. Seudeal, Ph.D.